https://ogma.newcastle.edu.au/vital/access/ /manager/Index ${session.getAttribute("locale")} 5 https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:52475 Wed 28 Feb 2024 15:33:43 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:54980 Wed 27 Mar 2024 15:13:43 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:45024 Wed 26 Oct 2022 15:30:38 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:45183 Wed 26 Oct 2022 14:32:09 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:27538 Wed 23 Feb 2022 16:06:32 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:45070 N = 53,032). Perinatal distress was measured using the EPDS (scores of 10–12) and probable perinatal depression was measured using the EPDS (scores of 13 or more). Logistic regression models that adjusted for confounding variables were used to investigate a range of psychosocial and obstetric determinants and perinatal distress and depression. Results: Eight percent of this cohort experienced antenatal distress and about 5 % experienced postnatal distress. Approximately 6 % experienced probable antenatal depression and 3 % experienced probable postnatal depression. Being from a culturally and linguistically diverse background (AOR = 2.0, 95% CI 1.8–2.3, P< 0.001), a lack of partner support (AOR = 2.9, 95% CI 2.3–3.7) and a maternal history of childhood abuse (AOR = 1.9, 95% CI 1.6–2.3) were associated with antenatal distress. These associations were similar in women with probable antenatal depression. Women who scored 10 to12 on antenatal EPDS assessment had a 4.5 times higher odds (95% CI 3.4–5.9, P< 0.001) of experiencing probable postnatal depression compared with women scoring 9 or less. Conclusion: Antenatal distress is more common than antenatal depressive symptoms and postnatal distress or depression. Antenatal maternal distress was associated with probable postnatal depression. Scale properties of the EPDS allows risk-stratification of women in the antenatal period, and earlier intervention with preventively focused programs. Prevention of postnatal depression could address a growing burden of illness and long-term complications for mothers and their infants.]]> Wed 22 Mar 2023 18:26:16 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:38684 Wed 17 Apr 2024 10:09:22 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:51050 Wed 16 Aug 2023 12:22:47 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:51715 Wed 13 Mar 2024 08:09:21 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:2177 Wed 11 Apr 2018 17:19:37 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:17016 Wed 11 Apr 2018 17:19:33 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:15776 Wed 11 Apr 2018 16:59:53 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:6807 Wed 11 Apr 2018 16:11:59 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:17013 Wed 11 Apr 2018 15:46:30 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:14774 Wed 11 Apr 2018 15:28:25 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:27198 Wed 11 Apr 2018 14:24:41 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:25212 Wed 11 Apr 2018 13:57:57 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:22229 90cm; 93%), age (>44 years; 79%), physical activity level (<150minwk^-1; 59%), family history of diabetes (39%) and previously high blood glucose levels (32%). Men with AUSDRISK scores ≥20 had higher (mean±SD) HbA_1C (6.0±0.4% [42±4.4mmol.mol^-1], P <0.001), FPG (5.3±0.6mmol.L^-1, P =0.001) and waist circumference (113.2±9.8cm, P =0.026) than men with scores of 12-15. Mean FPG for the sample was 5.0±0.6mmol.L^-1, whereas mean HbA_1C was 5.8±0.5% [40±5.5mmol.mol^-1]. Pre-diabetes prevalence was 70% and metabolic syndrome prevalence was 62%. Conclusions: The AUSDRISK tool identified men who were mostly older than 44, and had large waist circumferences and elevated HbA1C. These findings provide evidence supporting the usefulness of the AUSDRISK screening tool for T2DM screening in clinical and research settings.]]> Wed 11 Apr 2018 12:50:49 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:24290 Wed 11 Apr 2018 12:36:53 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:23626 Wed 11 Apr 2018 11:45:54 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:15190 Wed 11 Apr 2018 11:02:11 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:14003 Wed 11 Apr 2018 10:28:54 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:17462 Wed 11 Apr 2018 09:18:36 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:32778 Wed 07 Feb 2024 16:54:46 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:49595 Wed 06 Mar 2024 14:57:34 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:54171 Wed 06 Mar 2024 14:31:01 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:48980 Wed 06 Mar 2024 14:15:46 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:34475 Wed 06 Apr 2022 14:03:39 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:38126 Wed 04 Aug 2021 15:14:30 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:25739 Wed 02 Oct 2019 10:16:17 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:32861 Tue 31 Jul 2018 11:58:49 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:15503 Tue 24 Jul 2018 10:17:19 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:31265 Tue 24 Jul 2018 09:52:25 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:52965 Tue 14 Nov 2023 12:58:28 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:49885 Tue 13 Jun 2023 13:08:41 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:47053 Tue 13 Dec 2022 15:25:32 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:51614 Tue 12 Sep 2023 13:49:19 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:21934 Tue 11 Dec 2018 15:28:18 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:38190 Tue 10 Aug 2021 16:00:40 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:36562 Tue 09 Jun 2020 12:53:09 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:38413 Tue 07 Sep 2021 16:15:37 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:4345 Tue 05 Jun 2018 11:07:03 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:30456 Tue 01 May 2018 09:15:25 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:32457 Thu 27 Jan 2022 15:59:25 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:509 140/90 mmHg at the initial screening visit, 898 (24%) were not eligible for study entry after two further visits due to the elevated reading not being sustained. For both systolic and diastolic blood pressure recording, observed digit preference fell within 7 percentage points of the expected frequency. Protocol adherence, in terms of the required minimum blood pressure difference between the last two successive recordings, was 99.8%. These data suggest that adherence to blood pressure recording protocols and elimination of digit preferences can be achieved through appropriate training programs and quality control activities in large multi-centre community-based trials in general practice. Repeated blood pressure measurement prior to initial diagnosis and study entry is essential to appropriately characterize hypertension in these elderly patients.]]> Thu 25 Jul 2013 09:10:26 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:18 5 kg over 5 years) were highest for women who quit smoking (odds ratio = 2.94; 95% confidence interval, 2.17, 3.96). There were also independent relationships between the odds of gaining > 5 kg and lower levels of habitual physical activity, more time spent sitting, energy intake (but only in women with BMI > 25 at baseline), menopause transition, and hysterectomy. Discussion: The average weight gain equates with an energy imbalance of only about 10 kcal or 40 kJ per day, which suggests that small sustained changes in the modifiable behavioral variables could prevent further weight gain.]]> Thu 25 Jul 2013 09:10:09 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:165 Thu 25 Jul 2013 09:09:46 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:182 Thu 25 Jul 2013 09:09:30 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:29187 Thu 24 Mar 2022 11:31:49 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:13981 Thu 20 Sep 2018 15:01:52 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:38606 2 or a chronic health condition recruited from general practices was conducted. The arms included (1) BBL-GP, a web-based intervention augmented with an in-person diet and physical activity consultation; (2) a single clinician-led group, Lifestyle Modification Program (LMP); and (3) a web-based control. The primary outcome was the Australian National University Alzheimer Disease Risk Index Short Form (ANU-ADRI-SF). Results: Baseline assessments were conducted on 128 participants. A total of 125 participants were randomized to 3 groups (BBL-GP=42, LMP=41, and control=42). At immediate, week 18, week 36, and week 62 follow-ups, the completion rates were 43% (18/42), 57% (24/42), 48% (20/42), and 48% (20/42), respectively, for the BBL-GP group; 71% (29/41), 68% (28/41), 68% (28/41), and 51% (21/41), respectively, for the LMP group; and 62% (26/42), 69% (29/42), 60% (25/42), and 60% (25/42), respectively, for the control group. The primary outcome of the ANU-ADRI-SF score was lower for the BBL-GP group than the control group at all follow-ups. These comparisons were all significant at the 5% level for estimates adjusted for baseline differences (immediate: difference in means -3.86, 95% CI -6.81 to -0.90, P=.01; week 18: difference in means -4.05, 95% CI -6.81 to -1.28, P<.001; week 36: difference in means -4.99, 95% CI -8.04 to -1.94, P<.001; and week 62: difference in means -4.62, 95% CI -7.62 to -1.62, P<.001). Conclusions: A web-based multidomain dementia risk reduction program augmented with allied health consultations administered within the general practice context can reduce dementia risk exposure for at least 15 months. This study was limited by a small sample size, and replication on a larger sample with longer follow-up will strengthen the results.]]> Thu 18 Nov 2021 09:43:15 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:54266 Thu 15 Feb 2024 14:32:43 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:36055 Thu 13 Jan 2022 10:32:01 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:46986 Thu 06 Jul 2023 15:13:05 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:31327 Thu 03 Feb 2022 12:22:23 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:55246 Thu 02 May 2024 15:10:45 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:7767 Sat 24 Mar 2018 10:48:03 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:13753 Sat 24 Mar 2018 10:39:17 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:8629 Sat 24 Mar 2018 08:40:19 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:7459 Sat 24 Mar 2018 08:38:50 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:1878 Sat 24 Mar 2018 08:31:18 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:1369 Sat 24 Mar 2018 08:28:18 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:1449 5 kg over 5 years) were highest for women who quit smoking (odds ratio = 2.94; 95% confidence interval, 2.17, 3.96). There were also independent relationships between the odds of gaining >5 kg and lower levels of habitual physical activity, more time spent sitting, energy intake (but only in women with BMI > 25 at baseline), menopause transition, and hysterectomy. Discussion: The average weight gain equates with an energy imbalance of only about 10 kcal or 40 kJ per day, which suggests that small sustained changes in the modifiable behavioral variables could prevent further weight gain.]]> Sat 24 Mar 2018 08:28:11 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:16028 Sat 24 Mar 2018 08:21:18 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:14527 18 years. Types of intervention(s)/phenomena of interest: Intervention programs were required to have a parental component, to target eating and/or exercise behaviors for the prevention or treatment of obesity, and child weight status reported. Types of studies: All intervention studies were included in the review including: randomized controlled trials (RCTs); non-randomized controlled trials, longitudinal studies, cohort (both retrospective and prospective), case control and time series studies which had been conducted in a community setting. Types of outcomes: This review considered studies that included overweight/obesity related outcomes, eating behavior outcomes, physical activity behaviour outcomes, and sedentary behavior outcomes and constructs. Search strategy: A literature search of community-based parent-centred intervention studies to promote nutrition and physical activity for the prevention and treatment and of childhood overweight and obesity was performed in eight electronic databases dating from 1975 to April 2009. Methodological quality: Studies were critically appraised for methodological quality using standardized tools. Data collection: Data was extracted by one reviewer using a standardized data extraction form developed by the researchers and checked for accuracy and consistency by a second reviewer. Data synthesis: Data in relation to setting, methodology, intervention components and effect on weight, dietary intake and physical activity was extracted, and described in a narrative synthesis. Where possible a meta-analysis was undertaken. Results: Of the home-based interventions, five of nine studies reported statistically significant changes in anthropometric outcomes post intervention. Of the 10 studies in the before and after school care setting, seven reported a significant decrease in a weight-related outcome post intervention, with only one reporting an increase. Conclusions: Results from the review support the after-school setting as the most promising for community intervention setting for targeting parents as agents of change within child obesity prevention and treatment programs.]]> Sat 24 Mar 2018 08:19:46 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:11282 Sat 24 Mar 2018 08:12:43 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:12320 Sat 24 Mar 2018 08:11:37 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:10559 Sat 24 Mar 2018 08:08:23 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:18306 Sat 24 Mar 2018 08:04:40 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:18128 Sat 24 Mar 2018 08:04:28 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:21279 Sat 24 Mar 2018 07:54:41 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:5741 Sat 24 Mar 2018 07:45:02 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:5387 Sat 24 Mar 2018 07:43:55 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:109 Sat 24 Mar 2018 07:42:49 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:28813 Sat 24 Mar 2018 07:38:26 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:28656 n = 100) for five-months following hospital discharge after stroke (plus usual care) and compared with usual care (n = 101). Ethical approval was obtained to withhold information about the intervention and primary outcome from participants during the consent process. Results: No significant difference was seen in the proportion of participants with depression in the intervention group (1/88) vs. the control group (3/76) (relative risk 0·29, 95% confidence interval 0·03–2·71) at six-months. No significant differences were seen on Hospital Anxiety Depression Scale (HADS) depression and anxiety sub-scale scores, quality of life, or activities of daily living; however, many (47/100) responded positively to the postcards. Conclusions: Although this simple postcard intervention did not significantly reduce the proportion of participants experiencing high HADS depression sub-scale scores after stroke, it may be an effective way to engage with people after stroke following hospital discharge.]]> Sat 24 Mar 2018 07:37:13 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:28681 Sat 24 Mar 2018 07:30:08 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:22276 Sat 24 Mar 2018 07:17:41 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:23607 Sat 24 Mar 2018 07:13:29 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:52851 30%. For each group, an age–period– cohort model or generalised linear model with cigarette smoking exposure as a covariate was selected based on the model fit statistics and validation using observed data. The smoking-attributable fraction (SAF) was calculated for each smoking-related cancer using Australian smoking prevalence data and published relative risks. Results: Despite the decreasing mortality rates projected for the period 2015–2019 to 2040–2044 for both men and women, the overall number of smoking-related cancer deaths is estimated to increase by 28.7% for men and 35.8% for women: from 138 707 (77 839 men and 60 868 women) in 2015–2019 to 182 819 (100 153 men and 82 666 women) in 2040–2044. Over the period 2020–2044, there will be 254 583 cancer deaths (173 943 men and 80 640 women) directly attributable to smoking, with lung, larynx, oesophagus and oral (comprising lip, oral cavity and pharynx) cancers having the largest SAFs. Interpretation: Cigarette smoking will cause over 250 000 cancer deaths in Australia from 2020 to 2044. Continued efforts in tobacco control remain a public health priority, even in countries where smoking prevalence has substantially declined.]]> Mon 30 Oct 2023 09:54:19 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:38860 Mon 29 Jan 2024 17:51:04 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:34271 Mon 25 Feb 2019 14:55:32 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:32454 Mon 23 Sep 2019 10:58:08 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:32840 Mon 23 Sep 2019 10:38:27 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:53955 Mon 22 Jan 2024 17:03:26 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:35498 Mon 19 Aug 2019 12:04:34 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:20555 Mon 18 Mar 2019 12:45:01 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:40669 Mon 18 Jul 2022 08:25:13 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:55063 65%) of students. Most students (mean age = 17) did not know that early sexual debut (before 18 years) is a risk factor for cervical cancer (72%) and that a blood test cannot detect cervical cancer (71%). Students in later stages of senior high school education and those who received sexual health education from teachers and parents had significantly greater cervical cancer knowledge scores than their counterparts. Interactive effects showed that school-based sexual health education was associated with higher knowledge scores than home-based education among students. Conclusions: Most female senior high school students had gaps in knowledge about cervical cancer prevention. Finding new ways to strengthen the capacity of schools and parents to deliver accurate cervical cancer prevention information is warranted.]]> Mon 08 Apr 2024 12:39:07 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:50073 Fri 30 Jun 2023 11:20:20 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:42185 P<0.001). GAL3 levels were higher in MHD‐POS versus MHD‐NEG patients (7.7±2.3 versus 6.3±1.9 ng/mL, respectively; P<0.001). Both GAL3 and FSTL3 levels correlated with diastolic dysfunction and increased pulmonary artery systolic pressure but not with left ventricular mass. In multivariate models including all 3 biomarkers, only GAL3 remained associated with MHD (odds ratio: 1.30; 95% CI, 1.01–1.68; P=0.04). Conclusions: In young obese individuals without known cardiovascular disease, GAL3 is associated with the presence of preclinical MHD. GAL3 may be useful in screening for preclinical MHD and identifying individuals with increased risk of progression to obesity‐related heart failure with preserved ejection fraction.]]> Fri 26 Aug 2022 08:26:42 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:40356 Fri 22 Jul 2022 15:05:21 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:37575 Fri 19 Feb 2021 15:37:52 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:46399 313) and questionnaire-based breast cancer risk factors for women of European ancestry, using 72 284 cases and 80 354 controls from the Breast Cancer Association Consortium. Interactions were evaluated using standard logistic regression and a newly developed case-only method for breast cancer risk overall and by estrogen receptor status. After accounting for multiple testing, we did not find evidence that per-standard deviation PRS₃₁₃ odds ratio differed across strata defined by individual risk factors. Goodness-of-fit tests did not reject the assumption of a multiplicative model between PRS₃₁₃ and each risk factor. Variation in projected absolute lifetime risk of breast cancer associated with classical risk factors was greater for women with higher genetic risk (PRS₃₁₃ and family history) and, on average, 17.5% higher in the highest vs lowest deciles of genetic risk. These findings have implications for risk prevention for women at increased risk of breast cancer.]]> Fri 18 Nov 2022 14:15:23 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:27572 Fri 10 Mar 2023 19:00:19 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:45747 Fri 04 Nov 2022 10:26:56 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:45716 Fri 04 Nov 2022 09:31:08 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:42763 Fri 02 Sep 2022 09:01:20 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:49801 Fri 02 Jun 2023 17:06:43 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:51373 Fri 01 Sep 2023 13:41:09 AEST ]]>